Microbial genomes exhibit a high degree of plasticity (or variability) and any given microbial population (defined as a collection of closely-related individuals) is far more heterogenous in its genetic composition than previously assumed. High-throughput genome sequencing of entire populations now allows for a comprehensive observation of genome evolution on a molecular level. This approach is being employed to model organisms and communities, including Pseudoalteromonas tunicata, Phaeobacter inhibens and Pseudomonas aeruginosa, to understand their adaptation and evolution to conditions of environmental and medical relevance (McElroy PNAS USA 2014). This project also develops novel bioinformatics tool to process large volumes of next-generation sequencing data. For more information contact A/Prof. Torsten Thomas.